Erythropoiesisstimulating agents esas medical policy no. Achieve and maintain hemoglobin levels within the range of 10 to 12 gdl in the following conditions. Hematopoietic stimulants help your body make new white blood cells and help prevent infection after chemotherapy. Hematopoietic cell transplantation hct refers to a procedure in which hematopoietic stem cells. Hematopoietic agents workbook and casebook for goodman and. Hematology hematopoietic agents for the treatment of. Irradiation is repeated 3 hrs later for a total dose of 700r 1200r split dose irradiation is used to limit the non hematopoietic toxicity usually intestinal damage. All blood cell types arise from hematopoietic stem cells hscs that reside mainly in. Stenotrophomonas maltophilia colonization during allogeneic hematopoietic stem cell transplantation is associated.
Hematopoietic definition of hematopoietic by medical. Hematopoietic stem cell transplantation hsct overview. All cellular blood components are derived from haematopoietic stem cells. Preparative conditioning for allogeneic hematopoietic sct. Immunosuppressive agents antimicrobial agents fluid needs 1,500 ml x body surface area bsa 1222018 1222018 15 nutrient goals macris pc. Oct 16, 2018 a total of 229 pediatric patients, who underwent hsct between 1 january 2005 and 31 december 2015 at the university children hospital wuerzburg, were studied. Hematopoietic and lymphoid neoplasm coding manual published 2019. Please use the ndc drug lookup to find prior authorization pa forms guiding rules of the preferred drug list pdl. Medical nutrition therapy in hematopoietic cell transplantation. Casematched comparison with standard versus reduced intensity conditioning regimen in chronic myeloid leukemia patients. The conventional classical practice of allogeneic hct involves administration of cytotoxic agents e. Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytesthey are used in the treatment of anemias. Learn hematopoietic agents with free interactive flashcards.
The beneficial treatment effect in this procedure is due to a combination of initial eradication of malignant. Typically, the generic is preferred when available unless the brandname drug appears on the masshealth brand name preferred over generic drug list. Current uses and outcomes of hematopoietic stem cell transplantation. The clinical program shall have a written safety manual that includes. Hematopoietic comparisons for manual and database 2010, 2012, 2014 pdf, 742 kb note. Hematopoietic agents workbook and casebook for goodman.
Hematology hematopoietic agents for the treatment of anemias hematopoietic agent common uses what i need to know as a brand new nurse ferrous sulfate. Jul 19, 2018 materials, study design and definitions. It may make it less likely that you will have severe complications or need to be hospitalized. The factjacie international standards for hematopoietic cellular therapy. Shelanski, md,phd professor of pathology and cell biology. Hematopoietichematinic agents hematopoietics and hematinics also known as erythropoiesis stimulating agents esas are a covered nevada medicaid benefit for recipients who meet the following criteria. Hematology hematopoietic agents for the treatment of anemias. Leser m ed, oncology nutrition for clinical practice. For dosing instructions of combination agents administered with adcetris, see. University of michigan hematopoietic agents epogen or procrit epoetin alfa, aranesp darbepoetin some of the information needed to make a determination for coverage is not specifically requested on the michigan prior authorization request form. Hematopoesis is a lifelong process that involves the continuous formation and turnover of blood cells.
Hematopoietic medical definition merriamwebster medical. A model of hematopoietic bone marrow apoptosis during growth. Safety considerations in phase 1 trials joseph toerner, md, mph deputy director for safety. Ohio medicaid unified pdl effective january 1, 2020 page 1 ohio medicaid pharmacy benefit management program unified preferred drug list medicaid feeforservice and managed care plans.
We revisited the medical records of 264 patients with a diagnosis of aml, who underwent a first allohsct at our institution between january 2006 and march 2016 and extended the cohort to december 2016 up to overall 291 patients. Hematopoietic stem cells are rare bone marrow cells that manifest selfrenewal and lineage commitment, resulting in cells destined to differentiate into the 9 distinct bloodcell lineages. In addition to the material presented here, the 12th edition contains. As such, nearly 200 genes have been examined for roles in hsc function in knockout mice. Original article reduced intensity melphalan conditioning. How do i perform hematopoietic progenitor cell selection. Many of the changes observed in the hematopoietic system with age are due to alterations in hscs and committed progenitors. Pertaining to hematopoiesis, the production of all types of blood cells. Hematopoietic stem cell transplantation hsct is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood.
Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. Request pdf hematopoietic agents hematopoesis is a lifelong process that involves the continuous formation and turnover of blood cells. In the case where the prior authorization pa status column indicates pa, both the brand and generic if available require pa. Mice will be monitored to assure there is no acute illness. Irradiation is repeated 3 hrs later for a total dose of 700r 1200r split dose irradiation is used to limit the nonhematopoietic toxicity usually intestinal damage. Agerelated hematopoietic changes occur gradually over time, but can potentially be reversed. Hematopoietic cell transplantation hematopoietic cell transplantation hct refers to a procedure in which hematopoietic stem cells are infused to restore bone marrow function in cancer patients who receive bonemarrowtoxic doses of cytotoxic drugs with or without whole body radiation therapy. The finite life span of most mature blood cells requires their continuous replacement, a process termed hematopoiesis.
Howitreatpatientswhomobilizehematopoieticstemcellspoorly. Prior authorization list general information rightcare authorization requirement list effective january 1, 2020 3 1. All relevant data are within the paper and its supporting information files. For nonpreferred agents in this classcategory, patients must have had an inadequate response or have had a documented intolerance due to severe adverse reaction or contraindication to at least two preferred agents. Choose from 301 different sets of hematopoietic agents flashcards on quizlet. Hematopoietic comparison documents seer registrars. For the most part, this process occurs in the marrow cavities of the skull, vertebral bodies. The regulation of blood cell production is complex. Maintaining adequate blood cell production, as well as being able to meet increased demand, is in part under the control of a group of hormonelike glycoproteins that includes the hematopoietic growth factors and the interleukins. Aetna is the brand name used for products and services provided by one or more of the aetna group of subsidiary companies, including aetna life insurance company and its affiliates aetna. We collect clinical information before elective inpatient admissions andor selected ambulatory procedures and services take place. Hematopoietic definition of hematopoietic by medical dictionary. The aging hematopoietic system undergoes many changes.
Has the multiagent system approach been the only attempt done until now. Hematopoietic agents this chapter will be most useful after having a basic understanding of the material in chapter 37, hematopoietic agents. A total of 229 pediatric patients, who underwent hsct between 1 january 2005 and 31 december 2015 at the university children hospital wuerzburg, were studied. Reducedintensity conditioning ric refers to chemotherapy regimens that. If you have any questions, please submit a question to seer and choose hematopoietic rules as the subject. Haematopoietic stem cells hscs reside in the medulla of the bone bone marrow and have the unique ability to give rise to all of the different mature blood cell types and tissues.
However, asct is the standard of care in first line therapy for transplant eligible patients in the era of novel drugs. Issues cost treatment are raised by these agents, but the true clin ical value of hematopoietic growth factors needs to be studied more rigorously, with emphasis on quality of life. The hematopoietic and lymphoid neoplasm coding manual heme manual and the companion hematopoietic and lymphoid neoplasm database heme db are dedicated to the hard working cancer registrars across the world who meticulously identify, abstract, and code cancer data. University of michigan hematopoietic agents epogen or procrit epoetin alfa, aranesp darbepoetin some of the information needed to make a determination for coverage is not specifically requested on the michigan prior authorization request form for prescription drugs. Early and late complications following hematopoietic stem. Stenotrophomonas maltophilia colonization during allogeneic. Ohio medicaid pdl effective january 1, 2020 page 6 analgesic agents. Hematopoietic stem and progenitor cells stemcell technologies. The implementation of hematopoietic progenitor cell hpc selection is employed by some stem cell processing facilities to mitigate this complication. The process is regulated in part by hematopoietic growth factorsnaturally occurring hormones that stimulate the proliferation and differentiation of hematopoietic stem cells, and enhance function in the mature forms of those cells. During hematopoiesis, a small fraction of cells undergo cell death.
This chapter will be most useful after having a basic understanding of the material in chapter 37, hematopoietic agents. Hematopoietic stem cells hscs represent one of the first recognized somatic stem cell types. The cells undergo sequential divisions as they mature and the mature cells have limited life spans. Outcomes after autotransplants with the addition of novel agents and combinations for the treatment of multiple mye\. Patient data was obtained from the patient registry sap and from patient files and was then recorded in microsoft excel files microsoft office excel 2011. These immature myeloblasts expand in the bone marrow, peripheral blood, and other tissues, with a corresponding reduction in the production. Failure to achieve desired therapeutic outcomes with trial on 2 or more preferred agents o documented trial period for preferred agents o documented adeadr to preferred agents appropriate diagnosis appendix a appropriate participant age o mircera. Hematopoiesis is the process by which our bodies make red blood cells, white blood cells, and platelets.
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